ESPN
Nov 10, 2025, 06:08 PM ET
The Notre Dame and the Pittsburgh will start Saturday's action at noon, in a showdown of ranked opponents. Notre Dame has been undefeated since losing their first two games, and has climbed back into the top 10 of the College Football Playoff rankings. Meanwhile, Pitt has been the No. 11 passing offense since turning to Mason Heintschel at QB, and have won five games in a row to put themselves back in the ACC race. Pittsburgh will be where ESPN College Gameday sets up on Saturday morning to get the college football day started.
Afterward, there are three other matchups featuring ranked opponents. In the Big Ten, the Iowa Hawkeyes travel west for an appointment with the USC Trojans, while the SEC will feature Oklahoma-Alabama and Texas-Georgia. The latter matchup is a rematch of last season's SEC Championship game.
Current rankings below are from last week's College Football Playoff rankings, and will be updated Tuesday following the reveal at 8 p.m. on ESPN.
All times Eastern. For latest lines, go to ESPN BET

Clemson at No. 15 Louisville -3.5
Friday, 7:30 p.m., ESPN
Records: Clemson 4-5, 0-1 vs. AP teams; Louisville 7-2, 1-1 vs. AP teams
Opening Line: Louisville -3.5, O/U 51.5
Money line: Clemson (+135); Louisville (-155)
Over/Under: 50.5 (O -105, U -115)
FPI Projection Louisville by 1.2 points with a 55% probability to win game outright

Minnesota at No. 9 Oregon -24.5
Friday, 9 p.m., FOX
Records: Minnesota 6-3, 1-1 vs. AP teams; Oregon 8-1, 1-1 vs. AP teams
Line Movement Alert: Opened Oregon -21.5, O/U 44.5
Money line: Off
Over/Under: 43.5 (O -115, U -105)
FPI Projection Oregon by 25.4 points with a 96% probability to win game outright

Wisconsin at No. 2 Indiana -30.5
Saturday, Noon, BTN
Records: Wisconsin 3-6, 1-4 vs. AP teams; Indiana 10-0, 2-0 vs. AP teams
Opening Line: Indiana -30.5, O/U 43.5
Money line: Off
Over/Under: 44.5 (O -110, U -110)
FPI Projection Indiana by 28.7 points with a 97% probability to win game outright

South Carolina at No. 3 Texas A&M -18.5
Saturday, Noon, ESPN
Records: South Carolina 3-6, 0-5 vs. AP teams; Texas A&M 9-0, 3-0 vs. AP teams
Opening Line: Texas A&M -17.5, O/U 48.5
Money line: South Carolina (+1000); Texas A&M (-2000)
Over/Under: 47.5 (O -115, U -105)
FPI Projection Texas A&M by 12.5 points with a 85% probability to win game outright

No. 10 Notre Dame -10.5 at No. 24 Pittsburgh
Saturday, Noon, ABC
Records: Notre Dame 7-2, 1-2 vs. AP teams; Pittsburgh 7-2, 1-0 vs. AP teams
Opening Line: Notre Dame -11.5, O/U 56.5
Money line: Notre Dame (-425); Pittsburgh (+320)
Over/Under: 55.5 (O -105, U -115)
FPI Projection Notre Dame by 8.1 points with a 77% probability to win game outright

No. 21 Michigan -11.5 at Northwestern
Saturday, Noon, FOX
Records: Michigan 7-2, 0-1 vs. AP teams; Northwestern 5-4, 0-2 vs. AP teams
Opening Line: Michigan -10.5, O/U 40.5
Money line: Michigan (-550); Northwestern (+380)
Over/Under: 41.5 (O -105, U -115)
FPI Projection Michigan by 9 points with a 79% probability to win game outright

No. 12 Oklahoma at No. 4 Alabama -6.5
Saturday, 3:30 p.m., ABC
Records: Oklahoma 7-2, 3-1 vs. AP teams; Alabama 8-1, 4-0 vs. AP teams
Opening Line: Alabama -7.5, O/U 45.5
Money line: Oklahoma (+180); Alabama (-215)
Over/Under: 46.5 (O -105, U -115)
FPI Projection Alabama by 5.8 points with a 72% probability to win game outright

UCF at No. 8 Texas Tech -23.5
Saturday, 3:30 p.m., FOX
Records: UCF 4-5, 0-0 vs. AP teams; Texas Tech 9-1, 2-0 vs. AP teams
Opening Line: Texas Tech -23.5, O/U 47.5
Money line: UCF (+1300); Texas Tech (-4000)
Over/Under: 47.5 (O -115, U -105)
FPI Projection Texas Tech by 18.2 points with a 91% probability to win game outright

No. 14 Virginia at Duke -6.5
Saturday, 3:30 p.m., ESPN2
Records: Virginia 8-2, 1-0 vs. AP teams; Duke 5-4, 0-2 vs. AP teams
Opening Line: Duke -6.5, O/U 59.5
Money line: Virginia (+190); Duke (-225)
Over/Under: 57.5 (O -120, U EVEN)
FPI Projection Duke by 2.5 points with a 61% probability to win game outright

No. 17 Georgia Tech -16.5 at Boston College
Saturday, 3:30 p.m., ACC Network
Records: Georgia Tech 8-1, 1-0 vs. AP teams; Boston College 1-9, 0-2 vs. AP teams
Opening Line: Georgia Tech -16.5, O/U 57.5
Money line: Georgia Tech (-1000); Boston College (+550)
Over/Under: 58.5 (O -110, U -110)
FPI Projection Georgia Tech by 14.3 points with a 87% probability to win game outright

NC State at No. 18 Miami -15.5
Saturday, 3:30 p.m., ESPN
Records: NC State 5-4, 1-1 vs. AP teams; Miami 7-2, 3-0 vs. AP teams
Opening Line: Miami -14.5, O/U 55.5
Money line: NC State (+550); Miami (-900)
Over/Under: 55.5 (O -110, U -110)
FPI Projection Miami by 15 points with a 88% probability to win game outright

No. 20 Iowa at No. 19 USC -6.5
Saturday, 3:30 p.m.,
Records: Iowa 6-3, 0-3 vs. AP teams; USC 7-2, 1-2 vs. AP teams
Opening Line: USC -6.5, O/U 49.5
Money line: Iowa (+210); USC (-250)
Over/Under: 49.5 (O -115, U -105)
FPI Projection USC by 7.5 points with a 76% probability to win game outright

New Mexico State at No. 25 Tennessee -39.5
Saturday, 4:15 p.m., SEC Network
Records: New Mexico State 4-5, 0-1 vs. AP teams; Tennessee 6-3, 0-3 vs. AP teams
Opening Line: Tennessee -38.5, O/U 61.5
Money line: Off
Over/Under: 61.5 (O -115, U -105)
FPI Projection Tennessee by 38.8 points with a >99% probability to win game outright

Florida at No. 6 Ole Miss -16.5
Saturday, 7 p.m., ESPN
Records: Florida 3-6, 1-4 vs. AP teams; Ole Miss 9-1, 2-1 vs. AP teams
Line Movement Alert: Opened Ole Miss -13.5, O/U 52.5
Money line: Florida (+550); Ole Miss (-900)
Over/Under: 53.5 (O -115, U -105)
FPI Projection Ole Miss by 10 points with a 81% probability to win game outright

No. 13 Utah -10.5 at Baylor
Saturday, 7 p.m., ESPN2
Records: Utah 7-2, 2-2 vs. AP teams; Baylor 5-4, 1-1 vs. AP teams
Line Movement Alert: Opened Utah -7.5, O/U 60.5
Money line: Utah (-360); Baylor (+280)
Over/Under: 60.5 (O -105, U -115)
FPI Projection Utah by 8.7 points with a 79% probability to win game outright

Purdue at No. 23 Washington -16.5
Saturday, 7 p.m., FS1
Records: Purdue 2-8, 0-4 vs. AP teams; Washington 6-3, 1-1 vs. AP teams
Opening Line: Washington -15.5, O/U 52.5
Money line: Purdue (+600); Washington (-1000)
Over/Under: 53.5 (O -110, U -110)
FPI Projection Washington by 15.3 points with a 89% probability to win game outright

UCLA at No. 1 Ohio State -31.5
Saturday, 7:30 p.m., NBC
Records: UCLA 3-6, 1-1 vs. AP teams; Ohio State 9-0, 2-0 vs. AP teams
Opening Line: Ohio State -30.5, O/U 48.5
Money line: UCLA (+3500); Ohio State (-50000)
Over/Under: 48.5 (O -110, U -110)
FPI Projection Ohio State by 33.9 points with a 98% probability to win game outright

No. 11 Texas at No. 5 Georgia -6.5
Saturday, 7:30 p.m., ABC
Records: Texas 7-2, 2-1 vs. AP teams; Georgia 8-1, 2-1 vs. AP teams
Opening Line: Georgia -6.5, O/U 49.5
Money line: Texas (+180); Georgia (-215)
Over/Under: 48.5 (O -110, U -110)
FPI Projection Georgia by 2.3 points with a 60% probability to win game outright

Mississippi State at No. 22 Missouri -6.5
Saturday, 7:45 p.m., SEC Network
Records: Mississippi State 5-5, 1-4 vs. AP teams; Missouri 6-3, 0-3 vs. AP teams
Opening Line: Missouri -5.5, O/U 51.5
Money line: Mississippi State (+195); Missouri (-230)
Over/Under: 51.5 (O -115, U -105)
FPI Projection Missouri by 7.1 points with a 75% probability to win game outright

TCU at No. 7 BYU -6.5
Saturday, 10:15 p.m., ESPN
Records: TCU 6-3, 0-0 vs. AP teams; BYU 8-1, 1-1 vs. AP teams
Opening Line: BYU -4.5, O/U 51.5
Money line: TCU (+170); BYU (-200)
Over/Under: 52.5 (O -110, U -110)
FPI Projection BYU by 6.7 points with a 74% probability to win game outright
















































